Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 17/20 | 0.60 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.55 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545815 | 0.91 | MAOB (0.54) | GPR132 | |
| SCHEMBL8545786 | 0.90 | GPR132 (0.52) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL7907454 | 0.88 | GPR132 (0.54) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL7907451 | 0.88 | GPR132 (0.54) | GPR132CMKLR2CMKLR1 | |
| Water SCHEMBL7900960 | 0.87 | GPR132 (0.53) | GPR132CMKLR2CMKLR1 | |
| Water SCHEMBL7900958 | 0.87 | GPR132 (0.53) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL8549981 | 0.87 | MRGPRX4 (0.52) | GPR132 | |
| SCHEMBL8546398 | 0.86 | FFAR1 (0.46) | GPR132 | |
| SCHEMBL8545746 | 0.85 | GPR132 (0.51) | GPR132 | |
| SCHEMBL8547558 | 0.85 | SMPD1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |