Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752682 | 0.76 | MEN1 (0.48) | MAPTHSD11B1TLR8POLBGAA | |
| SCHEMBL8549611 | 0.76 | CYP19A1 (0.49) | MAPK14CYP3A4CACNA1BCACNA1GPOLB | |
| SCHEMBL920137 | 0.74 | PARP10 (0.51) | THRBIDO1LPAR1LPAR5 | |
| SCHEMBL3574617 | 0.74 | KDM4E (0.50) | MAPK14CYP3A4MAPTHSD11B1TLR8 | |
| SCHEMBL31490388 | 0.74 | KDM4E (0.50) | MAPK14CYP3A4MAPTHSD11B1TLR8 | |
| Formamide SCHEMBL8545827 | 0.73 | CARM1 (0.48) | MAPK14CYP3A4THRBIDO1GAA | |
| SCHEMBL7192577 | 0.73 | NCOA1 (0.49) | CYP3A4MAPTHSD11B1TLR8NPC1 | |
| SCHEMBL8545423 | 0.73 | SMN1; SMN2 (0.51) | THRBIDO1MAPTGAAKDM4E | |
| SCHEMBL12806565 | 0.73 | HSD11B1 (0.40) | HSD11B1TLR8NPC1RAB9APOLB | |
| SCHEMBL5936711 | 0.72 | TLR8 (0.46) | MAPTTLR8POLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |