Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920137 | 0.79 | PARP10 (0.51) | THRBIDO1LTA4HEPHX2 | |
| Formamide SCHEMBL8546795 | 0.78 | SLC2A1 (0.39) | CARM1PRMT6THRBIDO1ALDH1A1 | |
| SCHEMBL2218696 | 0.77 | THRB (0.64) | THRBIDO1ALDH1A1GAAHPGD | |
| Formamide SCHEMBL8546773 | 0.75 | S1PR1 (0.47) | GAAOPRM1 | |
| Formamide SCHEMBL8550226 | 0.75 | THRB (0.48) | THRBIDO1ALDH1A1HPGDTSHR | |
| SCHEMBL8545847 | 0.73 | MAPK14 (0.44) | CARM1PRMT6THRBIDO1GAA | |
| Formamide SCHEMBL8545672 | 0.71 | PARP15 (0.51) | HPGD | |
| SCHEMBL8545423 | 0.70 | SMN1; SMN2 (0.51) | THRBIDO1ALDH1A1GAAHTT | |
| SCHEMBL25199821 | 0.70 | THRB (0.53) | THRBIDO1ALDH1A1GAAHPGD | |
| SCHEMBL8550162 | 0.70 | F2 (0.50) | CARM1PRMT6THRBIDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |