Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696473 | 0.91 | SIGMAR1 (0.46) | HMOX1CYP19A1TBXAS1SIGMAR1CYP1A2 | |
| SCHEMBL8539454 | 0.78 | HRH3 (0.51) | SIGMAR1CYP2D6 | |
| SCHEMBL8543346 | 0.77 | SIGMAR1 (0.63) | CYP19A1TBXAS1SIGMAR1POLB | |
| SCHEMBL8698749 | 0.76 | HMOX1 (0.41) | HMOX1CYP19A1TBXAS1CYP1A2POLB | |
| SCHEMBL9030985 | 0.76 | HRH3 (0.51) | SIGMAR1CYP2D6 | |
| SCHEMBL27493109 | 0.74 | HRH3 (0.45) | SIGMAR1 | |
| SCHEMBL8539162 | 0.72 | SLC6A2 (0.49) | — | |
| SCHEMBL3160306 | 0.72 | CYP19A1 (0.71) | HMOX1CYP19A1TBXAS1CYP1A2POLB | |
| SCHEMBL7817195 | 0.72 | SIGMAR1 (0.59) | SIGMAR1POLB | |
| SCHEMBL27406758 | 0.72 | SIGMAR1 (0.59) | SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | claimed |