Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028593 | 0.89 | CNR1 (0.40) | SCN9ATYK2CNR2LPAR1TNF | |
| SCHEMBL9028568 | 0.88 | SCN9A (0.37) | SCN9ATYK2CNR2GPBAR1POLB | |
| SCHEMBL9028891 | 0.86 | LIMK1 (0.37) | SCN9ATYK2CNR2SLC22A12POLB | |
| SCHEMBL9028689 | 0.85 | SCN9A (0.37) | SCN9ATYK2CNR2GPBAR1SLC22A12 | |
| SCHEMBL8328842 | 0.84 | NPC1 (0.38) | NPC1POLB | |
| SCHEMBL9030025 | 0.84 | GPBAR1 (0.38) | SCN9ATYK2GPBAR1 | |
| SCHEMBL9027971 | 0.84 | CRHR1 (0.37) | LPAR1ROCK2 | |
| SCHEMBL9028966 | 0.83 | HPGD (0.36) | SCN9ATYK2CNR2NOTUMADAMTS5 | |
| SCHEMBL8549639 | 0.81 | GPBAR1 (0.37) | SCN9ACNR2GPBAR1P2RX7 | |
| SCHEMBL8550618 | 0.81 | LIPE (0.43) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |