Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780191 | 0.80 | ALDH1A1 (0.45) | GAAPOLBMAPTHPGDCYP1A2 | |
| SCHEMBL27699504 | 0.73 | CYP1A2 (0.42) | GAAPOLBMAPTHPGDCYP1A2 | |
| SCHEMBL10405098 | 0.70 | HPGD (0.55) | MAPTHPGDCYP1A2F3CHRNB2 | |
| SCHEMBL28426524 | 0.70 | HPGD (0.44) | GAAMAPTHPGDCYP1A2F3 | |
| SCHEMBL2773405 | 0.69 | ALDH1A1 (0.49) | POLBALDH1A1HTT | |
| SCHEMBL7946799 | 0.68 | HPGD (0.42) | GAAMAPTHPGDCYP1A2F3 | |
| SCHEMBL10739945 | 0.67 | HPGD (0.44) | GAAPOLBMAPTHPGDCYP1A2 | |
| SCHEMBL10734159 | 0.67 | HPGD (0.44) | GAAPOLBMAPTHPGDCYP1A2 | |
| SCHEMBL8541864 | 0.67 | HPGD (0.44) | GAAPOLBMAPTHPGDCYP1A2 | |
| SCHEMBL1756511 | 0.67 | AKR1C3 (0.43) | MAPTHPGDCYP1A2F3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343548-B1 | METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC FROM A DELIVERY MATRIX | BOSTON SCIENT LTD (BB) | 2012-03-28 | — | — | EP | disclosed |
| EP-1343548-A2 | METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC FROM A DELIVERY MATRIX | Boston Scientific Limited (BB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002043788-A2 | METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC FROM A DELIVERY MATRIX | BOSTON SCIENTIFIC LIMITED (BB) | 2002-06-06 | — | — | WO | disclosed |