Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922661 | 0.83 | FLT1 (0.42) | L3MBTL1HPGDKMT2AALDH1A1CYP1A2 | |
| SCHEMBL1922910 | 0.81 | MAPK1 (0.46) | L3MBTL1HPGDKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8545021 | 0.81 | FLT1 (0.45) | KMT2AALDH1A1CYP1A2CYP2C9FLT1 | |
| SCHEMBL29993431 | 0.81 | DGAT1 (0.58) | L3MBTL1KMT2AALDH1A1DGAT1FLT1 | |
| SCHEMBL4110083 | 0.81 | DGAT1 (0.58) | L3MBTL1KMT2AALDH1A1DGAT1FLT1 | |
| SCHEMBL8397291 | 0.80 | NPC1 (0.47) | HPGDKMT2AALDH1A1CYP1A2ALOX15 | |
| SCHEMBL11450051 | 0.79 | HPGD (0.60) | L3MBTL1HPGDKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8591280 | 0.79 | LPAR1 (0.43) | HPGDKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11771242 | 0.76 | ALDH1A1 (0.47) | HPGDKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29530881 | 0.75 | L3MBTL1 (0.47) | L3MBTL1HPGDKMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821255-A | REGULATING THE SECRETION OF CORTICOTROPIN, BETA-ENDORPHIN OR PEPTIDES DERIVED FROM PROOPIOMELANOCORTIN | SANOFI (FR) | 1998-10-13 | — | — | US | disclosed |
| EP-0659747-B1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1998-04-01 | — | — | EP | disclosed |
| EP-0576350-B1 | Branched alkylamino thiazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1997-10-29 | — | — | EP | disclosed |
| US-5602132-A | USEFUL IN TREATMENT OF PATHOLOGIES INVOLVING CORTICOTROPIN RELEASING FACTOR | SANOFI (FR) | 1997-02-11 | — | — | US | disclosed |
| CN-1127252-A | Branched-amino-sbustituted thiazoles, processes for their preparation and the pharmaceutical compositions which contain them | SANOFI SA (FR) | 1996-07-24 | — | — | CN | disclosed |
| US-5464847-A | Moduators of corticotropin releasing factor | ELF SANOFI (FR) | 1995-11-07 | — | — | US | disclosed |
| EP-0659747-A1 | Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1995-06-28 | — | — | EP | disclosed |
| EP-0576350-A1 | Branched alkylamino thiozole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-3946071-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-03-23 | — | — | US | disclosed |