Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451281 | 0.90 | HTT (0.70) | TTRALDH1A1HTTL3MBTL1MAPK1 | |
| SCHEMBL11342414 | 0.88 | SLC6A4 (0.47) | TTRALDH1A1HTTL3MBTL1MAPK1 | |
| SCHEMBL6158567 | 0.86 | DAO (0.52) | TTRDAO | |
| SCHEMBL9502693 | 0.86 | TTR (0.50) | TTRALDH1A1HTTL3MBTL1MAPK1 | |
| SCHEMBL510124 | 0.84 | LTA4H (0.61) | TTRLTA4HFFAR1 | |
| SCHEMBL1338731 | 0.83 | ST14 (0.48) | TTRALDH1A1LTA4HFFAR1 | |
| SCHEMBL8551187 | 0.83 | ST14 (0.48) | TTRALDH1A1LTA4HFFAR1 | |
| SCHEMBL32670327 | 0.81 | CARM1 (0.51) | TTRALDH1A1DPP4CARM1PRMT6 | |
| SCHEMBL9501898 | 0.79 | DHFR (0.50) | TTRALDH1A1HTTL3MBTL1MAPK1 | |
| SCHEMBL10855250 | 0.79 | HPGD (0.55) | TTRALDH1A1HTTL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |