Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338731 | 1.00 | ST14 (0.48) | ST14LTA4HTTRTSHRALDH1A1 | |
| SCHEMBL510124 | 0.90 | LTA4H (0.61) | LTA4HTTRTSHRCA1CA2 | |
| SCHEMBL2987196 | 0.90 | MAOB (0.54) | ST14LTA4HTTRMAOAMAOB | |
| SCHEMBL9505702 | 0.88 | SMN1; SMN2 (0.49) | ST14LTA4HTTRTSHRALDH1A1 | |
| SCHEMBL6158659 | 0.88 | MAPT (0.52) | ST14LTA4HMEN1KMT2ACA2 | |
| SCHEMBL2072044 | 0.88 | LTA4H (0.46) | ST14LTA4HMAOAMAOB | |
| SCHEMBL6161837 | 0.88 | TEAD4 (0.52) | ST14LTA4HTTRALDH1A1TDP1 | |
| SCHEMBL6157954 | 0.88 | LTA4H (0.54) | LTA4HTTRTSHRALDH1A1CYP3A4 | |
| SCHEMBL8549352 | 0.86 | ALDH1A1 (0.54) | ST14LTA4HTTRALDH1A1TDP1 | |
| SCHEMBL6158908 | 0.84 | LTA4H (0.61) | LTA4HTSHRALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |