Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355905 | 0.97 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3CXCL8KCNH2 | |
| SCHEMBL9516575 | 0.86 | L3MBTL1 (0.41) | SLC6A4SLC6A2SLC6A3CXCL8KCNH2 | |
| SCHEMBL8551189 | 0.86 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3KCNH2HRH1 | |
| SCHEMBL3139704 | 0.85 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3CXCL8RIPK1 | |
| SCHEMBL3157328 | 0.85 | CXCL8 (0.59) | SLC6A4SLC6A2SLC6A3CXCL8KCNH2 | |
| SCHEMBL3142433 | 0.84 | HRH1 (0.60) | SLC6A4SLC6A2SLC6A3HRH1RIPK1 | |
| SCHEMBL3155173 | 0.82 | HTR1B (0.44) | SLC6A4HRH1ALDH1A1 | |
| SCHEMBL8549354 | 0.81 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3KCNH2HRH1 | |
| SCHEMBL3150537 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3KCNH2HRH1 | |
| SCHEMBL11342414 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |