Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885446 | 0.88 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1KDM4EJAK2 | |
| SCHEMBL8546183 | 0.86 | SLC6A4 (0.46) | SLC6A2SLC6A3SLC6A4CXCL8KCNH2 | |
| SCHEMBL3355905 | 0.84 | SLC6A4 (0.47) | SLC6A2SLC6A3SLC6A4CXCL8KCNH2 | |
| SCHEMBL6848695 | 0.82 | KDM4E (0.54) | L3MBTL1MAPTNPSR1KDM4EJAK2 | |
| SCHEMBL8551628 | 0.76 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1KDM4ELMNA | |
| SCHEMBL8551189 | 0.74 | SLC6A4 (0.53) | L3MBTL1SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL19175412 | 0.73 | ALDH1A1 (0.47) | L3MBTL1MAPTNPSR1KDM4EJAK2 | |
| SCHEMBL7889403 | 0.73 | MAPK1 (0.51) | L3MBTL1MAPTNPSR1KDM4EJAK2 | |
| SCHEMBL6478845 | 0.73 | L3MBTL1 (0.43) | L3MBTL1MAPTNPSR1KDM4EJAK2 | |
| SCHEMBL7562011 | 0.73 | MAPT (0.52) | L3MBTL1MAPTNPSR1KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423870-B1 | DIBENZODIOXAZECINE AND DIBENZODIOXAAZACYCLOUNDECINE DERIVATIVES | Akzo Nobel N.V. (NL) | 1993-07-14 | — | — | EP | disclosed |
| US-5106839-A | DIBENZODIOXAZECINE AND DIBENZODIOXAAZACYCLOUNDECINE DERIVATIVES | AKZO N.V. (NL) | 1992-04-21 | — | — | US | disclosed |
| EP-0423870-A1 | Dibenzodioxazecine and dibenzodioxaazacycloundecine derivatives | Akzo Nobel N.V. (NL) | 1991-04-24 | — | — | EP | disclosed |