Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9674029 | 0.99 | MAPT (0.34) | MAPTCYP17A1RPS6KA3CYP11B1CYP11B2 | |
| SCHEMBL7616004 | 0.82 | BCHE (0.44) | CYP17A1RPS6KA3SLC6A2BCHEACHE | |
| SCHEMBL8539328 | 0.81 | BCHE (0.51) | MAPTCYP11B1CYP11B2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8544423 | 0.80 | ROCK1 (0.42) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9738851 | 0.78 | BCHE (0.50) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL9671998 | 0.77 | BCHE (0.49) | BCHEACHE | |
| SCHEMBL9738706 | 0.76 | BCHE (0.47) | BCHE | |
| Hydrochloric Acid SCHEMBL9671926 | 0.76 | BCHE (0.46) | BCHE | |
| SCHEMBL8540339 | 0.75 | BCHE (0.42) | MAPTRPS6KA3SLC6A2BCHEACHE | |
| SCHEMBL8546208 | 0.71 | MAPT (0.36) | MAPTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |