Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635601 | 0.91 | KDM4E (0.50) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL18712914 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL18179341 | 0.83 | LMNA (0.36) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL3164186 | 0.81 | GAA (0.63) | ALDH1A1LMNAKDM4ESMN1; SMN2CYP2A6 | |
| SCHEMBL24514898 | 0.81 | PARP10 (0.41) | ALDH1A1LMNAKDM4ESMN1; SMN2CYP2A6 | |
| SCHEMBL18914481 | 0.80 | TTR (0.34) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL20091516 | 0.80 | TTR (0.34) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL20091525 | 0.79 | TTR (0.33) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL18914695 | 0.79 | RXRA (0.34) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL8311249 | 0.79 | TTR (0.58) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |