Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IL18 | Q14116 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 13/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582194 | 0.89 | PARP15 (0.57) | FFAR1FFAR4PARP15PARP10PARP2 | |
| SCHEMBL3138833 | 0.85 | PARP15 (0.53) | FFAR1FFAR4PARP15PARP10PARP2 | |
| SCHEMBL7074972 | 0.83 | EPAS1 (0.44) | FFAR1FFAR4EPAS1VEGFA | |
| SCHEMBL921025 | 0.83 | CYP19A1 (0.51) | FFAR1FFAR4PARP15PARP10PARP2 | |
| SCHEMBL8852392 | 0.82 | PARP15 (0.63) | PARP15PARP10PARP2CYP19A1KDM4E | |
| SCHEMBL7041250 | 0.82 | PARP15 (0.63) | PARP15PARP10PARP2CYP19A1KDM4E | |
| SCHEMBL30689372 | 0.80 | CYP19A1 (0.57) | FFAR1FFAR4PARP15PARP10PARP2 | |
| SCHEMBL27368527 | 0.80 | CYP19A1 (0.57) | FFAR1FFAR4PARP15PARP10PARP2 | |
| SCHEMBL852039 | 0.80 | MEN1 (0.53) | PARP15PARP10PARP2CYP19A1KDM4E | |
| SCHEMBL8546604 | 0.80 | AR (0.51) | PARP15PARP10PARP2CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |