Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547013 | 0.86 | HPGD (0.57) | LMNANPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL27537790 | 0.86 | NPC1 (0.59) | TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8550262 | 0.83 | NPC1 (0.53) | TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8549654 | 0.83 | CARM1 (0.51) | LMNANPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL8549404 | 0.83 | HTR2C (0.49) | LMNANPC1RAB9A | |
| SCHEMBL8546499 | 0.81 | HPGD (0.51) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL8549624 | 0.79 | HPGD (0.49) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8550343 | 0.76 | HSD17B10 (0.46) | LMNATSHR | |
| SCHEMBL1990363 | 0.74 | NPC1 (0.69) | NPC1RAB9A | |
| SCHEMBL24011467 | 0.74 | CASR (0.62) | LMNATSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |