Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547013 | 0.93 | HPGD (0.57) | HPGDMAPK14GAAHTTNPC1 | |
| SCHEMBL27537790 | 0.87 | NPC1 (0.59) | L3MBTL1ALDH1A1GAASGMS2NPC1 | |
| SCHEMBL8546499 | 0.87 | HPGD (0.51) | HPGDMAPK14ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8549624 | 0.85 | HPGD (0.49) | HPGDMAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8550262 | 0.84 | NPC1 (0.53) | ALDH1A1GAASGMS2NPC1RAB9A | |
| SCHEMBL8546557 | 0.83 | LMNA (0.53) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8549404 | 0.79 | HTR2C (0.49) | HPGDL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL8550343 | 0.77 | HSD17B10 (0.46) | HPGDL3MBTL1ALDH1A1LMNA | |
| SCHEMBL1990363 | 0.75 | NPC1 (0.69) | L3MBTL1ALDH1A1NPC1RAB9ACA2 | |
| SCHEMBL690027 | 0.75 | NPC1 (0.59) | ALDH1A1NPC1RAB9ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |