Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10156824 | 0.89 | ALDH1A1 (0.48) | LGMNNR4A1ALDH1A1POLBKMT2A | |
| SCHEMBL16440144 | 0.84 | ALDH1A1 (0.43) | LGMNALDH1A1POLBKMT2AMAPT | |
| SCHEMBL25515887 | 0.83 | HTR3E (0.46) | LGMNALDH1A1POLBKMT2AMAPT | |
| SCHEMBL15358685 | 0.82 | NR4A1 (0.61) | NR4A1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL10036161 | 0.81 | NR4A1 (0.50) | NR4A1ALDH1A1POLBKMT2AMAPT | |
| SCHEMBL31312869 | 0.81 | MAPT (0.59) | LGMNNR4A1ALDH1A1POLBKMT2A | |
| SCHEMBL10127901 | 0.81 | MAPT (0.59) | LGMNNR4A1ALDH1A1POLBKMT2A | |
| SCHEMBL16437256 | 0.81 | ALDH1A1 (0.40) | LGMNALDH1A1POLBKMT2AMAPT | |
| SCHEMBL77893 | 0.81 | GAA (0.61) | LGMNNR4A1ALDH1A1MAPTGAA | |
| SCHEMBL15244255 | 0.81 | NR4A1 (0.47) | NR4A1ALDH1A1POLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487491-B2 | Diamino heterocyclic carboxamide compound | ASTELLAS PHARMA INC. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | LGMN 3983/4885NR4A1 1959/4885ALDH1A1 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.