Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 8/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PRF1 | P14222 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78883 | 0.84 | CYP3A4 (0.53) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL854481 | 0.84 | CYP3A4 (0.53) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL30743756 | 0.79 | CYP3A4 (0.49) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL24822259 | 0.79 | CYP3A4 (0.49) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL854918 | 0.78 | CYP3A4 (0.47) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL24822260 | 0.78 | CYP3A4 (0.51) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL13412837 | 0.77 | CYP3A4 (0.63) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL20570609 | 0.74 | CYP3A4 (0.47) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL9732073 | 0.74 | MAPT (0.53) | CYP3A4MAPTLMNAGAAMAOA | |
| SCHEMBL29559672 | 0.74 | MAPT (0.53) | CYP3A4MAPTLMNAGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |