Sugi Predict

Sugi Predict / Compounds / SCHEMBL78883

SCHEMBL78883

SCHEMBL78883

O=C1OCc2cc(Cl)c(Cl)cc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.53
▸ MAPT P10636 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ GAA P10253 1/20 0.50
▸ MAOA P21397 7/20 0.48
▸ MAOB P27338 6/20 0.48
▸ NPC1 O15118 1/20 0.47
▸ RECQL P46063 1/20 0.44
▸ PRF1 P14222 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ PPIA P62937 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.41
▸ TYMS P04818 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ KCNJ1 P48048 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24822259 0.86 CYP3A4 (0.49) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL30743756 0.86 CYP3A4 (0.49) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL854665 0.84 CYP3A4 (0.47) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL24822260 0.84 CYP3A4 (0.51) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL13412837 0.84 CYP3A4 (0.63) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL8386388 0.79 CYP3A4 (0.42) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL23340442 0.76 MAOA (0.39) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL29470781 0.75 MAOA (0.62) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL854490 0.75 MAOA (0.62) CYP3A4MAPTLMNAGAAMAOA
SCHEMBL855289 0.75 MAPT (0.61) CYP3A4MAPTLMNAGAAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132112-A1 COMPOUNDS CTXT PTY LTD (AU) 2026-05-14 — — US disclosed
EP-4077318-B1 BENZIMIDAZOLE DIMERS AS MODULATORS OF STING CTXT PTY LTD (AU) 2025-10-15 — — EP disclosed
US-12435075-B2 Compound, film, sensor, and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-10-07 — — US disclosed
US-12415785-B2 Compound modulators of sting CTXT PTY LTD (AU) 2025-09-16 — — US disclosed
CN-114981265-B Compounds of formula (I) CTXT私人有限公司 2025-01-03 — — CN disclosed
EP-4174063-A1 COMPOUND, FILM, SENSOR, AND ELECTRONIC DEVICE Samsung Electronics Co., Ltd. (KR) 2023-05-03 — — EP disclosed
CN-116023369-A Compound, membrane, sensor and electronic device 三星电子株式会社 2023-04-28 — — CN disclosed
US-20230125778-A1 COMPOUND, FILM, SENSOR, AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 — — US disclosed
US-20230125778-A1 COMPOUND, FILM, SENSOR, AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 — — US disclosed
US-20230125778-A1 COMPOUND, FILM, SENSOR, AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-04-27 — — US disclosed
EP-1611098-A1 COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF GLAXO GROUP LIMITED (GB) 2006-01-04 — — EP disclosed
WO-2004089897-A1 COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF GLAXO GROUP LIMITED (GB) 2004-10-21 — — WO disclosed
US-20040192612-A1 Caspase inhibitors and uses thereof VERTEX PHARMACEUTICALS INCORPORATED 2004-09-30 — — US disclosed
WO-2004058718-A1 4-OXO-3-(1-OXO-1H-ISOQUINOLIN-2-YLACETYLAMINO)-PENTANOIC ACID ESTER AND AMIDE DERIVATIVES AND THEIR USE AS CASPASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2004-07-15 — — WO disclosed
US-20040072850-A1 Caspase inhibitors and uses thereof VERTEX PHARMACEUTICALS INCORPORATED 2004-04-15 — — US disclosed
WO-2004002961-A1 CASPASE INHIBITORS AND USES THEREOF VERTEX PHARMACEUTICALS INCORPORATED (US) 2004-01-08 — — WO disclosed
EP-0399818-B1 Diarylstyrylquinoline diacids MERCK FROSST CANADA INC (CA) 1995-08-16 — — EP disclosed
US-5204358-A Antiallergens; antiinflammatory agents; treatment of asthma, rhinitis, bronchitis and skin diseases MERCK FROSST CANADA, INC. (CA) 1993-04-20 — — US disclosed
US-5104882-A Leukotriene antagonists MERCK FROSST CANADA, INC. (CA) 1992-04-14 — — US disclosed
EP-0399818-A1 Diarylstyrylquinoline diacids MERCK FROSST CANADA INC. (CA) 1990-11-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125778-A1 COMPOUND, FILM, SENSOR, AND ELECTRONIC DEVICE HAX1, CYP19A1, ESR1 CYP3A4 481/4885MAPT 3060/4885LMNA 2988/4885
US-20040072850-A1 Caspase inhibitors and uses thereof CASP1, CASP5, CASP2 CYP3A4 344/4885MAPT 2050/4885LMNA 148/4885
US-12415785-B2 Compound modulators of sting STING1, IRF3, MAVS CYP3A4 4741/4885MAPT 4334/4885LMNA 2531/4885
US-20040192612-A1 Caspase inhibitors and uses thereof CASP1, CASP3, CASP5 CYP3A4 1032/4885MAPT 367/4885LMNA 712/4885
US-20260132112-A1 COMPOUNDS STING1, IRF3, CGAS CYP3A4 3315/4885MAPT 2960/4885LMNA 2322/4885
US-12435075-B2 Compound, film, sensor, and electronic device HAX1, CYP19A1, ESR1 CYP3A4 481/4885MAPT 3060/4885LMNA 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.