Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548872 | 0.93 | POLB (0.43) | POLBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8552730 | 0.88 | POLB (0.41) | POLBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8471818 | 0.88 | PSD (0.41) | POLBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8547908 | 0.87 | POLB (0.41) | POLBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8552758 | 0.86 | KIF11 (0.42) | NTRK1CTSSMAPK1KIF11CTSK | |
| SCHEMBL8549675 | 0.84 | ADORA1 (0.46) | CTSSMAPK1KIF11CTSKLOXL2 | |
| SCHEMBL8773215 | 0.83 | CYP1A2 (0.50) | POLBMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8550852 | 0.83 | KIF11 (0.39) | NTRK1CTSSMAPK1KIF11CTSK | |
| SCHEMBL8552573 | 0.81 | TRPV1 (0.37) | NTRK1CTSSMAPK1KIF11CTSK | |
| SCHEMBL8551508 | 0.79 | TRPV1 (0.36) | NTRK1CTSSMAPK1KIF11CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | disclosed |