Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551508 | 0.88 | TRPV1 (0.36) | TRPV1KIF11CTSSCTSKLOXL2 | |
| SCHEMBL8552758 | 0.87 | KIF11 (0.42) | TRPV1KIF11CTSSCTSKLOXL2 | |
| SCHEMBL8548872 | 0.87 | POLB (0.43) | TRPV1KIF11CTSSCTSKLOXL2 | |
| SCHEMBL8549675 | 0.85 | ADORA1 (0.46) | TRPV1KIF11CTSSCTSKLOXL2 | |
| SCHEMBL8550852 | 0.83 | KIF11 (0.39) | TRPV1KIF11CTSSCTSKLOXL2 | |
| SCHEMBL8546808 | 0.81 | POLB (0.43) | KIF11CTSSCTSKLOXL2MAPK1 | |
| SCHEMBL8552730 | 0.80 | POLB (0.41) | CTSSCTSKLOXL2NTRK1 | |
| SCHEMBL8471818 | 0.80 | PSD (0.41) | CTSSLOXL2NTRK1 | |
| SCHEMBL8553832 | 0.78 | TRPV1 (0.43) | TRPV1KIF11CTSSCTSKSCN9A | |
| SCHEMBL8547908 | 0.77 | POLB (0.41) | CTSSCTSKLOXL2SCN9ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | disclosed |