Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548872 | 0.92 | POLB (0.43) | POLBCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8471818 | 0.89 | PSD (0.41) | POLBCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8546808 | 0.88 | POLB (0.43) | POLBCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8547908 | 0.86 | POLB (0.41) | POLBCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8552758 | 0.85 | KIF11 (0.42) | CTSSNTRK1LOXL2CTSK | |
| SCHEMBL8773215 | 0.84 | CYP1A2 (0.50) | POLBCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8549675 | 0.83 | ADORA1 (0.46) | CTSSLOXL2CTSKADORA2A | |
| SCHEMBL8550852 | 0.81 | KIF11 (0.39) | CTSSNTRK1LOXL2CTSK | |
| SCHEMBL8552573 | 0.80 | TRPV1 (0.37) | CTSSNTRK1LOXL2CTSK | |
| SCHEMBL8551508 | 0.78 | TRPV1 (0.36) | CTSSNTRK1LOXL2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | disclosed |