Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547751 | 0.91 | CARM1 (0.45) | CARM1PRMT6HTR2ACCR3 | |
| SCHEMBL8547957 | 0.91 | CARM1 (0.45) | CARM1PRMT6HTR2ACCR3 | |
| SCHEMBL8546422 | 0.84 | CARM1 (0.40) | CARM1PRMT6GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL8547951 | 0.84 | CARM1 (0.40) | CARM1PRMT6GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL8547945 | 0.82 | GRIN2B (0.45) | CARM1PRMT6GRIN2B | |
| SCHEMBL8548234 | 0.82 | GRIN2B (0.45) | CARM1PRMT6GRIN2B | |
| SCHEMBL8546419 | 0.82 | GRIN2B (0.45) | CARM1PRMT6GRIN2B | |
| SCHEMBL8546122 | 0.82 | LMNA (0.37) | GRIN2B | |
| SCHEMBL8542975 | 0.80 | MAOA (0.49) | GRIN2B | |
| SCHEMBL8548011 | 0.80 | GRIN2B (0.62) | GRIN2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |