Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548572 | 0.88 | EGFR (0.71) | MAPK1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL8975149 | 0.87 | HTT (0.71) | MAPK1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL7505545 | 0.83 | CCNC (0.63) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL8543093 | 0.81 | HTT (0.49) | MAPK1HTTCNR1CNR2PIK3CD | |
| SCHEMBL8547638 | 0.80 | MAPK1 (0.55) | MAPK1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL9921509 | 0.78 | PIK3CD (0.85) | MAPK1HTTCNR1CNR2PIK3CD | |
| SCHEMBL11846406 | 0.77 | KDM4E (0.63) | MAPK1SMN1; SMN2HTTPIK3CDPIK3R1 | |
| SCHEMBL8543007 | 0.77 | HTT (0.77) | MAPK1SMN1; SMN2HTTLMNAAPP | |
| SCHEMBL15923256 | 0.76 | EGFR (0.70) | MAPK1SMN1; SMN2HTTLMNAAPP | |
| SCHEMBL3979500 | 0.75 | KDM4E (0.77) | MAPK1SMN1; SMN2HTTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |