Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CCNC | P24863 | 2/20 | 0.54 |
| ▸ | CDK8 | P49336 | 2/20 | 0.54 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.54 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548572 | 0.88 | EGFR (0.71) | MAPK1HTTLMNAEGFRAPP | |
| SCHEMBL21162358 | 0.81 | EGFR (0.54) | MAPK1HTTLMNAEGFRAPP | |
| SCHEMBL8548141 | 0.80 | MAPK1 (0.62) | MAPK1HTTLMNAEGFRAPP | |
| SCHEMBL11250079 | 0.80 | PIK3CD (0.73) | MAPK1HTTLMNAEGFRSMN1; SMN2 | |
| SCHEMBL9921379 | 0.80 | HTT (0.65) | MAPK1HTTLMNAEGFRAPP | |
| SCHEMBL11249399 | 0.79 | LMNA (0.75) | MAPK1HTTLMNAEGFRSMN1; SMN2 | |
| SCHEMBL9921373 | 0.79 | CLK4 (0.63) | MAPK1HTTLMNAEGFRAPP | |
| SCHEMBL8548720 | 0.79 | HTT (0.69) | MAPK1HTTLMNAEGFRAPP | |
| SCHEMBL11265490 | 0.78 | LMNA (0.70) | MAPK1HTTLMNAEGFRSMN1; SMN2 | |
| SCHEMBL157421 | 0.78 | NFKB1 (0.63) | MAPK1HTTLMNAEGFRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| CN-1035825-A | Quinazoline derivant | LILLY CO ELI (US) | 1989-09-27 | — | — | CN | disclosed |