Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368943 | 0.87 | MAPT (0.37) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL7374791 | 0.83 | MMP1 (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1HSPA5 | |
| SCHEMBL7364097 | 0.82 | MMP1 (0.51) | MMP1MMP2MMP3 | |
| SCHEMBL7360514 | 0.77 | MMP1 (0.44) | ALDH1A1RAB9ATP53NPC1LMNA | |
| SCHEMBL7358380 | 0.74 | MMP1 (0.39) | MMP1MMP2MMP3 | |
| SCHEMBL8749681 | 0.74 | MMP1 (0.47) | MMP1MMP2MMP3 | |
| SCHEMBL7358017 | 0.73 | MMP1 (0.61) | MMP1MMP2MMP3 | |
| SCHEMBL6417502 | 0.73 | MMP1 (0.50) | MMP1MMP2MMP3 | |
| SCHEMBL7374561 | 0.71 | MAPT (0.37) | ALDH1A1HTTKMT2AMAPTMEN1 | |
| SCHEMBL7370348 | 0.70 | MMP2 (0.46) | HTTSMN1; SMN2LMNAMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740652-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1998-05-06 | — | — | EP | claimed |