Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.47 |
| ▸ | MMP3 | P08254 | 7/20 | 0.46 |
| ▸ | MMP2 | P08253 | 6/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MMP7 | P09237 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | FCER2 | P06734 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417502 | 0.93 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7364097 | 0.92 | MMP1 (0.51) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7358017 | 0.87 | MMP1 (0.61) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7360514 | 0.86 | MMP1 (0.44) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL6412867 | 0.77 | MMP3 (0.51) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7358380 | 0.76 | MMP1 (0.39) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7364461 | 0.76 | FCER2 (0.47) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7365448 | 0.75 | MMP1 (0.55) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8548294 | 0.74 | ALDH1A1 (0.37) | MMP1MMP3MMP2 | |
| SCHEMBL6412851 | 0.73 | MMP1 (0.39) | MMP1MMP3MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691382-A | ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |
| EP-0667770-B1 | INHIBITION OF TNF PRODUCTION | BRITISH BIOTECH PHARM (GB) | 1997-03-19 | — | — | EP | disclosed |