SCHEMBL8548307

SCHEMBL8548307

C=CC(=O)Nc1ccc(OCC)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 5/20 0.68
LMNA P02545 3/20 0.65
POLB P06746 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
CYP1A2 P05177 2/20 0.65
TDP1 Q9NUW8 1/20 0.65
ALDH1A1 P00352 3/20 0.63
MAPT P10636 6/20 0.62
NPC1 O15118 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
EGFR P00533 1/20 0.61
RAB9A P51151 1/20 0.61
KDM4E B2RXH2 2/20 0.55
HTT P42858 1/20 0.55
MAPK1 P28482 1/20 0.55
MAP2K7 O14733 1/20 0.54
F13A1 P00488 1/20 0.54
TGM1 P22735 1/20 0.54
TGM3 Q08188 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468299 0.95 TGM2 (0.62) TGM2LMNAPOLBMEN1KMT2A
SCHEMBL30445926 0.86 KMT2A (0.69) LMNAPOLBMEN1KMT2ACYP1A2
SCHEMBL10717674 0.84 THRA (0.63) TGM2
SCHEMBL11227015 0.83 KMT2A (0.65) LMNAPOLBMEN1KMT2ACYP1A2
SCHEMBL19854525 0.83 THRA (0.66) TGM2
SCHEMBL29036641 0.83 THRA (0.66) TGM2
SCHEMBL28310060 0.83 TGM2 (0.67) TGM2LMNAEGFRF13A1TGM1
SCHEMBL10700566 0.82 MEN1 (0.62) TGM2LMNAPOLBMEN1KMT2A
SCHEMBL23343645 0.81 EGFR (0.63) LMNAPOLBMEN1KMT2ACYP1A2
SCHEMBL5037362 0.81 MAP2K7 (0.59) TGM2LMNAPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702673-B1 BENZ(B)AZEPINE-2,5-DIONES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS ZENECA LTD (GB) 1998-02-25 EP claimed
EP-4630407-A1 2-METHYL-2-(1-METHYLCYCLOHEXYL)PROPANAMIDE DERIVATIVES AND 1-(TERT-BUTYL)-CYCLOHEXANE-1-CARBOXAMIDE DERIVATIVES FOR USE IN UMAMI FLAVOR COMPOSITIONS International Flavors & Fragrances, Inc. (US) 2025-10-15 EP disclosed
US-20190176459-A1 POSITIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 US disclosed
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 US disclosed
EP-0702673-B1 BENZ(B)AZEPINE-2,5-DIONES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS ZENECA LTD (GB) 1998-02-25 EP disclosed
EP-0409565-A1 Rubber composition useful for tires SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-23 EP disclosed