SCHEMBL19854525

SCHEMBL19854525

C=CC(=O)Nc1ccc(OCCCCCCCC)cc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.66
THRB P10828 1/20 0.66
FAAH O00519 14/20 0.60
S1PR1 P21453 2/20 0.59
S1PR3 Q99500 2/20 0.59
TGM2 P21980 1/20 0.59
GAA P10253 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
NAMPT P43490 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29036641 1.00 THRA (0.66) THRATHRBFAAHS1PR1S1PR3
SCHEMBL10717674 0.99 THRA (0.63) THRATHRBFAAHS1PR1S1PR3
SCHEMBL20370406 0.86 TGM2 (0.55) THRATHRBFAAHS1PR1S1PR3
SCHEMBL8733275 0.84 FAAH (0.64) FAAHS1PR1S1PR3GAAL3MBTL1
SCHEMBL24168619 0.83 TGM2 (0.52) THRATHRBTGM2
SCHEMBL8548307 0.83 TGM2 (0.68) TGM2
SCHEMBL10808118 0.83 ZDHHC2 (0.69) TGM2
SCHEMBL10806715 0.83 ZDHHC2 (0.69) TGM2
SCHEMBL10806059 0.83 ZDHHC2 (0.69) TGM2
SCHEMBL28310060 0.82 TGM2 (0.67) TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 THRA 3929/4885THRB 3939/4885FAAH 3511/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 THRA 3929/4885THRB 3939/4885FAAH 3511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.