Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.49 |
| ▸ | PTPRF | P10586 | 2/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837628 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL8837627 | 0.82 | CA1 (0.56) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL8837655 | 0.78 | CA1 (0.55) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL17358252 | 0.74 | CA1 (0.54) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL9706667 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL2181057 | 0.73 | CA1 (1.00) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL30362278 | 0.73 | CA1 (1.00) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL8548172 | 0.70 | TSHR (0.51) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL8507951 | 0.69 | CA1 (0.68) | ALDH1A1KDM4EPOLBHSD17B10CA1 | |
| SCHEMBL30748712 | 0.69 | CA1 (0.68) | ALDH1A1KDM4ETSHRHSD17B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840734-A1 | SUBSTITUTED ARYL SULPHONYL AMINO (THIO) CARBONYL TRIAZOLIN(THI)ONES | BAYER AG (DE) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997003980-A1 | SUBSTITUTED ARYL SULPHONYL AMINO (THIO) CARBONYL TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-06 | — | — | WO | disclosed |
| US-5597779-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| US-5552368-A | Sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1996-09-03 | — | — | US | disclosed |
| US-5519148-A | CHEMICAL INTERMEDIATES FOR HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1996-05-21 | — | — | US | disclosed |
| US-5489695-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5412107-A | Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| US-5286709-A | Sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5209771-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0496701-A1 | Sulfonylureas as herbizides | CIBA-GEIGY AG (CH) | 1992-07-29 | — | — | EP | disclosed |