Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548691 | 1.00 | PTGER4 (0.49) | PTGER4HRH3PTGER2CTSKLTA4H | |
| SCHEMBL8544615 | 0.92 | CTSK (0.47) | CTSK | |
| SCHEMBL8544621 | 0.92 | CTSK (0.47) | CTSK | |
| SCHEMBL8543314 | 0.89 | CTSK (0.53) | CTSK | |
| SCHEMBL8543316 | 0.89 | CTSK (0.53) | CTSK | |
| SCHEMBL8549483 | 0.88 | CTSK (0.56) | CTSK | |
| SCHEMBL8549474 | 0.88 | CTSK (0.56) | CTSK | |
| SCHEMBL8548482 | 0.88 | CTSK (0.46) | HRH3CTSKHDAC1HDAC2HDAC3 | |
| SCHEMBL8548486 | 0.88 | CTSK (0.46) | HRH3CTSKHDAC1HDAC2HDAC3 | |
| SCHEMBL8548835 | 0.86 | CTSK (0.49) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |