Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548482 | 1.00 | CTSK (0.46) | CTSKKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8545352 | 0.90 | KMT2A (0.46) | CTSKKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8545349 | 0.90 | KMT2A (0.46) | CTSKKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8544621 | 0.89 | CTSK (0.47) | CTSKKMT2AMEN1ALDH1A1 | |
| SCHEMBL8544615 | 0.89 | CTSK (0.47) | CTSKKMT2AMEN1ALDH1A1 | |
| SCHEMBL8543314 | 0.89 | CTSK (0.53) | CTSKKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8543316 | 0.89 | CTSK (0.53) | CTSKKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8549474 | 0.88 | CTSK (0.56) | CTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL8549483 | 0.88 | CTSK (0.56) | CTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL8548689 | 0.88 | PTGER4 (0.49) | CTSKHRH3HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |