Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.55 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548807 | 1.00 | GPR132 (0.55) | GPR132MBTPS1NOTUMNAMPTPSMB5 | |
| SCHEMBL8548804 | 0.89 | ALDH1A1 (0.49) | GPR132MBTPS1NOTUMNAMPTPSMB5 | |
| SCHEMBL8548808 | 0.89 | ALDH1A1 (0.49) | GPR132MBTPS1NOTUMNAMPTPSMB5 | |
| SCHEMBL8549718 | 0.87 | HSD17B10 (0.61) | GPR132NOTUMNAMPTPSMB5HSD17B10 | |
| SCHEMBL8549726 | 0.87 | HSD17B10 (0.61) | GPR132NOTUMNAMPTPSMB5HSD17B10 | |
| SCHEMBL5711200 | 0.85 | MBTPS1 (0.67) | MBTPS1PSMB5HSD17B10SMN1; SMN2GAA | |
| SCHEMBL11324889 | 0.85 | MBTPS1 (0.67) | MBTPS1PSMB5HSD17B10SMN1; SMN2GAA | |
| SCHEMBL6443067 | 0.80 | GPR132 (0.58) | GPR132ADAMTS4CYP3A4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6445549 | 0.79 | GPR132 (0.57) | GPR132ADAMTS4CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8543392 | 0.78 | NOTUM (0.50) | GPR132NOTUMNAMPTPSMB5ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574135-B1 | Process for producing peptide derivatives and salts thereof | JAPAN ENERGY CORP (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5644028-A | Process for producing peptide derivatives and salts therefor | JAPAN ENERGY CORPORATION (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0574135-A1 | Process for producing peptide derivatives and salts thereof | JAPAN ENERGY CORPORATION (JP) | 1993-12-15 | — | — | EP | disclosed |