Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548808 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NOTUMNAMPTCYP2C19CYP2C9 | |
| SCHEMBL8548803 | 0.89 | GPR132 (0.55) | ALDH1A1NOTUMNAMPTCYP2C19GPR132 | |
| SCHEMBL8548807 | 0.89 | GPR132 (0.55) | ALDH1A1NOTUMNAMPTCYP2C19GPR132 | |
| SCHEMBL17996008 | 0.86 | CYP2C9 (0.57) | ALDH1A1CYP2C19CYP2C9PSMB5HSD17B10 | |
| SCHEMBL8549726 | 0.84 | HSD17B10 (0.61) | ALDH1A1NOTUMNAMPTCYP2C19GPR132 | |
| SCHEMBL8549718 | 0.84 | HSD17B10 (0.61) | ALDH1A1NOTUMNAMPTCYP2C19GPR132 | |
| SCHEMBL8547954 | 0.78 | CASP3 (0.50) | MBTPS1 | |
| SCHEMBL8547949 | 0.78 | CASP3 (0.50) | MBTPS1 | |
| SCHEMBL10872087 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL10872082 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP2C19CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574135-B1 | Process for producing peptide derivatives and salts thereof | JAPAN ENERGY CORP (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5644028-A | Process for producing peptide derivatives and salts therefor | JAPAN ENERGY CORPORATION (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0574135-A1 | Process for producing peptide derivatives and salts thereof | JAPAN ENERGY CORPORATION (JP) | 1993-12-15 | — | — | EP | disclosed |