Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545058 | 0.88 | RAB9A (0.80) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8546815 | 0.86 | RAB9A (0.69) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL9162673 | 0.86 | RAB9A (0.69) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8541109 | 0.86 | RAB9A (0.67) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8542022 | 0.86 | RAB9A (0.59) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8542920 | 0.86 | RAB9A (0.57) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8547151 | 0.85 | RAB9A (0.58) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8548739 | 0.85 | RAB9A (0.69) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8546894 | 0.84 | LMNA (0.64) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL9383475 | 0.84 | LMNA (0.58) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |