Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540692 | 0.93 | RAB9A (0.65) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL9383475 | 0.92 | LMNA (0.58) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL9383480 | 0.91 | RAB9A (0.55) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8548739 | 0.88 | RAB9A (0.69) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8543820 | 0.88 | RAB9A (0.62) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL9304615 | 0.87 | RAB9A (0.53) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8548873 | 0.86 | RAB9A (0.60) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8544698 | 0.86 | RAB9A (0.61) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8545631 | 0.85 | MAPK14 (0.52) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8545058 | 0.85 | RAB9A (0.80) | RAB9ANPC1TSHRL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |