Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | CA4 | P22748 | 6/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169911 | 0.90 | PTGS2 (0.53) | MAOAMAOBCA1CA2CA4 | |
| SCHEMBL8551541 | 0.87 | PTGS2 (0.48) | CA1CA2PTGS2CA9CA12 | |
| SCHEMBL6169927 | 0.79 | PTGS2 (0.45) | MAOAMAOBCA1CA2CA4 | |
| SCHEMBL6169873 | 0.79 | PTGS2 (0.51) | MAOAMAOBCA1CA2CA4 | |
| SCHEMBL6170883 | 0.79 | PTGS2 (0.51) | MAOAMAOBCA1CA2CA4 | |
| SCHEMBL5822486 | 0.78 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8593289 | 0.78 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6167881 | 0.78 | PTGS2 (0.62) | MAOAMAOBCA1CA2CA4 | |
| SCHEMBL6170394 | 0.77 | CA1 (0.54) | MAOAMAOBCA1CA2CA4 | |
| SCHEMBL6170551 | 0.77 | CA1 (0.54) | MAOAMAOBCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |