Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 14/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822486 | 0.96 | PTGS2 (0.54) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL6169532 | 0.88 | PTGS2 (0.55) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL8551541 | 0.83 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6169911 | 0.80 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5732493 | 0.78 | PTGS2 (0.51) | PTGS2PTGS1CDK2ABCB11ALDH1A1 | |
| SCHEMBL5698527 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8548917 | 0.78 | MAOA (0.45) | PTGS2PTGS1 | |
| SCHEMBL4888033 | 0.77 | PTGS2 (0.53) | PTGS2PTGS1CDK2 | |
| SCHEMBL6168610 | 0.77 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6170005 | 0.76 | PTGS2 (0.50) | PTGS2PTGS1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |