Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548917 | 0.87 | MAOA (0.45) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL8593289 | 0.83 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6169911 | 0.82 | PTGS2 (0.53) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL5822486 | 0.79 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL5733857 | 0.77 | NR4A2 (0.50) | PTGS2PTGS1CA2SOS1CA12 | |
| SCHEMBL8477368 | 0.73 | PTGS2 (0.57) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL8474970 | 0.72 | PTGS2 (0.58) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL6167944 | 0.72 | PTGS2 (0.46) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL6172024 | 0.72 | PTGS2 (0.54) | PTGS2PTGS1CA2CA12CA1 | |
| SCHEMBL6169873 | 0.71 | PTGS2 (0.51) | PTGS2PTGS1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |