Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549101 | 1.00 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL8549085 | 0.85 | POLB (0.48) | ALDH1A1GAAMAPTHPGDTDP1 | |
| SCHEMBL8549093 | 0.85 | POLB (0.48) | ALDH1A1GAAMAPTHPGDTDP1 | |
| SCHEMBL8543316 | 0.84 | CTSK (0.53) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL8543314 | 0.84 | CTSK (0.53) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL8549106 | 0.83 | FKBP1A (0.48) | ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8548300 | 0.81 | NPC1 (0.48) | ALDH1A1MAPTNPSR1CTSKMEN1 | |
| SCHEMBL8548308 | 0.81 | NPC1 (0.48) | ALDH1A1MAPTNPSR1CTSKMEN1 | |
| SCHEMBL8544794 | 0.81 | NPSR1 (0.47) | ALDH1A1GAAMAPTNPSR1CTSK | |
| SCHEMBL8544789 | 0.81 | NPSR1 (0.47) | ALDH1A1GAAMAPTNPSR1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |