SCHEMBL8549219

SCHEMBL8549219

CC(O)OCCN1C(=O)C2CCCCC2C1=O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TP53 P04637 1/20 0.36
ATM Q13315 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17532412 0.74 ALDH1A1 (0.53) HTTRAB9AALDH1A1SMN1; SMN2TP53
SCHEMBL8549222 0.73 HTT (0.42) HTTRAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL22035557 0.73 HTT (0.49) HTTRAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL29324951 0.71 ALDH1A1 (0.47) HTTRAB9AALDH1A1SMN1; SMN2
SCHEMBL17549818 0.71 ALDH1A1 (0.47) HTTRAB9AALDH1A1SMN1; SMN2
SCHEMBL1147309 0.71 ALDH1A1 (0.47) HTTRAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL17532509 0.71 HTT (0.47) HTTRAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL208342 0.71 HTT (0.43) HTTRAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL17532416 0.70 ALDH1A1 (0.50) HTTRAB9AALDH1A1SMN1; SMN2LMNA
SCHEMBL3790254 0.70 MGLL (0.53) HTTRAB9AALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed