Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549380 | 1.00 | KEAP1 (0.47) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL8587030 | 0.78 | KMT2A (0.50) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL3866300 | 0.78 | KEAP1 (0.47) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL3866295 | 0.78 | KEAP1 (0.47) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL8549912 | 0.75 | SIGMAR1 (0.33) | KMT2AMEN1 | |
| SCHEMBL8549909 | 0.75 | SIGMAR1 (0.33) | KMT2AMEN1 | |
| Dinotefuran SCHEMBL28854297 | 0.73 | NAMPT (0.31) | — | |
| SCHEMBL6903269 | 0.71 | KEAP1 (0.52) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL6903267 | 0.71 | KEAP1 (0.52) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL6188391 | 0.71 | KEAP1 (0.44) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1099418-C | Tetrahydro-3-furanyl methylamine | MITSUI CHEMICALS INC (JP) | 2003-01-22 | — | — | CN | disclosed |
| CN-1046508-C | (tetrahydro-3-furanyl) methylamine derivatives, insecticides containing the same and intermediates thereof | MITSUI TOATSU CHEMICALS (JP) | 1999-11-17 | — | — | CN | disclosed |
| CN-1220991-A | Tetrahydro-3-furanyl methylamine | MITSUI CHEMICALS INC (JP) | 1999-06-30 | — | — | CN | disclosed |
| EP-0649845-B1 | Furanyl insecticide | MITSUI CHEMICALS INC (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5532365-A | NITROGUANIDINE COMPOUNDS AS INSECTICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-02 | — | — | US | disclosed |
| CN-1112556-A | Furanyl pesticide | MITSUI TOATSU CHEMICALS (JP) | 1995-11-29 | — | — | CN | disclosed |
| US-5434181-A | FOR USE IN AGRICULTURAL CHEMICALS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0649845-A1 | Furanyl insecticide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-04-26 | — | — | EP | disclosed |