Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903267 | 1.00 | KEAP1 (0.52) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL3866300 | 0.80 | KEAP1 (0.47) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL3866295 | 0.80 | KEAP1 (0.47) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL6188391 | 0.76 | KEAP1 (0.44) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL4812101 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2USP2KDM4EHPGDTP53 | |
| SCHEMBL8145696 | 0.73 | NAMPT (0.33) | — | |
| SCHEMBL8145694 | 0.73 | NAMPT (0.33) | — | |
| SCHEMBL18393466 | 0.73 | NAMPT (0.33) | — | |
| SCHEMBL8587030 | 0.72 | KMT2A (0.50) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E | |
| SCHEMBL8549382 | 0.71 | KEAP1 (0.47) | KEAP1NFE2L2SMN1; SMN2USP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153545-B1 | Prevention of pest feed harm on a fibrous product | SUMITOMO CHEMICAL CO (JP) | 2004-09-01 | — | — | EP | disclosed |