Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548228 | 0.82 | KMT2A (0.59) | LMNASMN1; SMN2GAAPOLBTSHR | |
| SCHEMBL7325645 | 0.82 | F2 (0.60) | LMNASMN1; SMN2PTPN1GAAMETAP2 | |
| SCHEMBL8542455 | 0.79 | POLB (0.65) | LMNASMN1; SMN2GAAPOLBTSHR | |
| SCHEMBL7330175 | 0.78 | F2 (0.67) | LMNAGAAPOLBKDM4EMAPT | |
| SCHEMBL8543524 | 0.76 | F2 (0.73) | LMNASMN1; SMN2HTR6PIK3CDPIK3CA | |
| SCHEMBL8752452 | 0.75 | PGR (0.67) | LMNASMN1; SMN2GAAHTR6MEN1 | |
| SCHEMBL5124637 | 0.75 | LMNA (0.72) | LMNASMN1; SMN2POLBALDH1A1THRB | |
| SCHEMBL5387842 | 0.75 | LMNA (0.72) | LMNASMN1; SMN2POLBALDH1A1THRB | |
| SCHEMBL6038132 | 0.74 | ALDH1A1 (0.51) | LMNASMN1; SMN2GAAPOLBMEN1 | |
| SCHEMBL4822277 | 0.74 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2GAAHTR6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |