Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838949 | 0.92 | KMT2A (0.74) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8928129 | 0.89 | GAA (0.54) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8098121 | 0.87 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8747121 | 0.87 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7279469 | 0.86 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7279475 | 0.86 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL11735352 | 0.86 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL13369886 | 0.82 | KMT2A (0.62) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL10841849 | 0.82 | MTNR1A (0.62) | KMT2AALDH1A1MAPT | |
| SCHEMBL8549452 | 0.82 | KMT2A (0.61) | KMT2AMEN1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |