Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652368 | 0.89 | KMT2A (0.54) | ALDH1A1KMT2AGAANPSR1LMNA | |
| SCHEMBL6024157 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL6748121 | 0.80 | PKM (0.51) | ALDH1A1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL63779 | 0.78 | KMT2A (0.64) | ALDH1A1KMT2AGAANPSR1LMNA | |
| SCHEMBL2643475 | 0.75 | ALDH1A1 (0.47) | ALDH1A1PTGS2KMT2AGAAMAPT | |
| SCHEMBL2665963 | 0.75 | LMNA (0.56) | ALDH1A1KMT2AGAANPSR1LMNA | |
| SCHEMBL18016057 | 0.74 | KMT2A (0.59) | ALDH1A1PTGS2KMT2AGAANPSR1 | |
| SCHEMBL2225281 | 0.73 | PHGDH (0.43) | ALDH1A1ENPP2PTGS2KMT2AGAA | |
| SCHEMBL5091783 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2AGAANPSR1RECQL | |
| SCHEMBL19859189 | 0.73 | CA12 (0.46) | ALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726243-A | Mild solid-phase synthesis of aligned, branched triple-helical peptides | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-03-10 | — | — | US | disclosed |