Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545172 | 0.92 | AOC3 (0.54) | AOC3ITGB3ITGA2BGRM5 | |
| SCHEMBL8550212 | 0.85 | DRD3 (0.55) | GRM5 | |
| SCHEMBL8549557 | 0.84 | GRM5 (0.49) | AOC3ITGB3ITGA2BGRM5MAOA | |
| SCHEMBL8548927 | 0.83 | ITGB3 (0.53) | AOC3ITGB3ITGA2BGRM5MAOA | |
| SCHEMBL8543792 | 0.82 | AOC3 (0.47) | AOC3ITGB3ITGA2BGRM5MAOA | |
| SCHEMBL8547139 | 0.82 | MAOA (0.53) | AOC3ITGB3ITGA2BGRM5MAOA | |
| SCHEMBL8549697 | 0.80 | MAOA (0.48) | AOC3ITGB3ITGA2BGRM5MAOA | |
| SCHEMBL8548454 | 0.79 | GRM5 (0.55) | AOC3ITGB3ITGA2BGRM5 | |
| SCHEMBL8543655 | 0.79 | ITGB3 (0.54) | AOC3ITGB3ITGA2BMAOAMAOB | |
| SCHEMBL8543334 | 0.79 | ITGB3 (0.48) | AOC3ITGB3ITGA2BGRM5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526402-B1 | Heteroaryl substituted hydroxylamine derivatives as lipoxygenase inhibitors | CIBA GEIGY AG (CH) | 1998-01-21 | — | — | EP | disclosed |
| US-5350761-A | Lipoxygenase inhibitors as antiinflammatory agents and antiallergens | CIBA-GEIGY CORPORATION (US) | 1994-09-27 | — | — | US | disclosed |
| US-5334600-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |
| US-5260316-A | Lipoxygenase inhibitor | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0526402-A1 | Heteroaryl substituted hydroxylamine derivatives as lipoxygenase inhibitors | CIBA-GEIGY AG (CH) | 1993-02-03 | — | — | EP | disclosed |