Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547416 | 0.78 | MAPT (0.41) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10691483 | 0.74 | FFAR1 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8546335 | 0.74 | HSD17B10 (0.44) | ALDH1A1HSD17B10LMNAMAPTTRPM8 | |
| SCHEMBL8545180 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8547337 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8618272 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SMN1; SMN2NPC1LMNA | |
| SCHEMBL8551529 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SMN1; SMN2NPC1LMNA | |
| SCHEMBL8546712 | 0.72 | L3MBTL1 (0.45) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10692209 | 0.71 | NPC1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8549517 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |