Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547337 | 0.92 | ALDH1A1 (0.43) | ALDH1A1LMNANPC1RAB9ATRPM8 | |
| SCHEMBL8546689 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1NPC1RAB9A | |
| SCHEMBL8546642 | 0.87 | TRPM8 (0.40) | ALDH1A1LMNAMEN1NPC1RAB9A | |
| SCHEMBL8545437 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNAMEN1NPC1RAB9A | |
| SCHEMBL8545180 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNANPC1RAB9ATRPM8 | |
| SCHEMBL8545401 | 0.83 | TRPM8 (0.40) | ALDH1A1LMNAMEN1NPC1RAB9A | |
| SCHEMBL8548073 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1NPC1RAB9A | |
| SCHEMBL8546335 | 0.74 | HSD17B10 (0.44) | ALDH1A1LMNAMEN1KMT2ATRPM8 | |
| SCHEMBL9035936 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNANPC1RAB9ATRPM8 | |
| SCHEMBL10689661 | 0.74 | ALDH1A1 (0.60) | ALDH1A1LMNAMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |