Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333119 | 0.93 | ALDH1A1 (0.53) | TDP1ALDH1A1SMN1; SMN2MAPTTRIM24 | |
| SCHEMBL25333237 | 0.91 | TDP1 (0.56) | TDP1KMOALDH1A1MAPTLMNA | |
| SCHEMBL7762056 | 0.91 | LMNA (0.50) | TDP1KMOALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3303519 | 0.89 | ALDH1A1 (0.50) | TDP1KMOALDH1A1KMT2AGAA | |
| SCHEMBL25332266 | 0.89 | TDP1 (0.44) | TDP1KMOALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15809138 | 0.85 | TDP1 (0.62) | TDP1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL875857 | 0.85 | POLB (0.50) | TDP1ALDH1A1MAPTCHEK2RAB9A | |
| SCHEMBL3122711 | 0.84 | MAOB (0.56) | TDP1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL3302672 | 0.82 | FDFT1 (0.42) | TDP1KMOALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6142827 | 0.82 | TDP1 (0.48) | TDP1ALDH1A1KMT2AGAATRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |